What does Sicario have to do with Sabrina the Teenage Witch?

In response to Josh Brolin being cast in Deadpool 2, Ryan Reynolds tweeted the following:
The fuck, Fox! You can't play 2 characters in the same universe!! Josh Brolin was in Sicario and I was in Sabrina The Teenage Witch.
I feel like there's a joke here I'm not getting. How are Sicario and Sabrina the Teenage Witch at all related?
Best Answer
That was a joke, as noticed by so many. From hollywoodreporter
Josh Brolin's casting as Cable in Fox's Deadpool 2 has been greeted with both joy and confusion online. After all, doesn't Brolin already play Thanos in the Marvel Cinematic Universe? Is that even allowed? (The answer to both: Yes!)
Deadpool star Ryan Reynolds played up those fan anxieties with a tone-perfect tweet.
"The f—, Fox! You can't play 2 characters in the same universe!! Josh Brolin was in Sicario and I was in Sabrina The Teenage Witch," he tweeted Wednesday.
(For the record, Brolin was not in Sabrina the Teenage Witch and Deadpool is not in the same universe as Avengers.)
Ryan just played with the fan confusion.
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